Drug Information

Herpes-Zoster Vaccine for Shingles

Herpes-Zoster Vaccine for Shingles

British Columbia Specific Information

Shingles is a painful rash caused by the varicella zoster virus. The shingles vaccine is the best way you can protect yourself against the virus. For more information about the shingles vaccine, see HealthLinkBC File #111 Shingles Vaccine or visit the ImmunizeBC Shingles web page.

Examples

Generic Name Brand Name
herpes-zoster vaccine Zostavax

Shingles  (herpes zoster) is a viral infection  of the nerve roots  that occurs when the virus that causes chickenpox  starts up again in your body. The shingles vaccine (herpes-zoster vaccine) is given by injection into the layer of fat under your skin (subcutaneous).

How It Works

When you receive the shingles vaccine, your body reacts by producing antibodies to fight against the herpes zoster virus.

Why It Is Used

Herpes zoster vaccine can prevent shingles or reduce pain and other symptoms in people who get shingles. The vaccine is recommended for adults age 60 and over who have not received the chickenpox (varicella) vaccine. 1, 2 It is available to adults age 50 and older. They can get one dose, whether or not they’ve had shingles before.

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Shingles vaccine is not recommended for:

  • People younger than 50 years of age.
  • Some people with impaired immune systems.
  • People who are taking high doses of corticosteroids  by mouth. People who are taking low doses or taking the medications by inhalation (such as people withasthma ) may be able to take the shingles vaccine.
  • People with severe short-term (acute) illnesses. For these people, shingles vaccination should be postponed until they feel better.
  • People who are allergic to gelatin or the antibiotic neomycin. The shingles vaccine contains small amounts of gelatin and neomycin.

How Well It Works

Herpes zoster vaccine prevents shingles in about 5 out of 10 of people who receive the vaccine. But the vaccine can reduce pain and other symptoms in people who get shingles after receiving the vaccine. 2

What To Think About

The vaccine is less effective in preventing shingles the older a person gets. A person who receives the vaccine at 60 years of age is less likely to get shingles than someone who receives it at 80 years of age. But pain and other symptoms of shingles infection are often reduced in people who have received the vaccine.

 

References

Citations

  1. National Advisory Committee on Immunization (2010). Statement on the recommended use of herpes zoster vaccine. Canada Communicable Disease Report, 36(ACS-1): 1–19. Also available online: http://origin.phac-aspc.gc.ca/publicat/ccdr-rmtc/10vol36/acs-1/index-eng.php.
  2. Centers for Disease Control and Prevention (2008). Prevention of herpes zoster: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR, 57(Early Release): 1–30. Also available online: http://www.cdc.gov/mmwr/PDF/rr/rr57e0515.pdf. [Erratum in MMWR, 57(28): 779. Also available online: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5728a5.htm.]