General Articles

Bacitracin, neomycin, polymyxin B, and pramoxin

U.S. BRAND NAMES — Neosporin® + Pain Relief Ointment [OTC]; Tri Biozene [OTC]

PHARMACOLOGIC CATEGORY
Antibiotic, Topical

DOSING: ADULTS — Topical: Apply 1-3 times/day to infected areas; cover with sterile bandage if needed

DOSING: PEDIATRIC — Topical: Children ≥ 2 years: Refer to adult dosing.

DOSING: ELDERLY — Refer to adult dosing.

DOSAGE FORMS — Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Ointment, topical: Bacitracin 500 units, neomycin 3.5 mg, polymyxin B 10,000 units, and pramoxine hydrochloride 10 mg (15 g, 30 g)
Neosporin® + Pain Relief Ointment: Bacitracin 500 units, neomycin 3.5 mg, polymyxin B 10,000 units, and pramoxine hydrochloride 10 mg per g (15 g, 30 g)
Tri Biozene: Bacitracin 500 units, neomycin 3.5 mg, polymyxin B 10,000 units, and pramoxine hydrochloride 10 mg per g (15 g)

DOSAGE FORMS: CONCISE
Ointment, topical: Bacitracin 500 units, neomycin 3.5 mg, polymyxin B 10,000 units, and pramoxine 10 mg (15 g, 30 g)
Neosporin® + Pain Relief Ointment [OTC]: Bacitracin 500 units, neomycin 3.5 mg, polymyxin B 10,000 units, and pramoxine 10 mg (15 g, 30 g)
Tri Biozene: Bacitracin 500 units, neomycin 3.5 mg, polymyxin B 10,000 units, and pramoxine 10 mg (15 g)

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GENERIC EQUIVALENT AVAILABLE — Yes

USE — Prevention and treatment of susceptible superficial topical infections and provide temporary relief of pain or discomfort

CONTRAINDICATIONS — Hypersensitivity to bacitracin, neomycin, polymyxin B, pramoxine, or any component of the formulation

WARNINGS / PRECAUTIONS
Other warnings/precautions:

May 2010
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